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Allopurinol is a xanthine oxidase inhibitor which decreases the amount of uric acid produced in the body. It is given to prevent the accumulation of uric acid that can cause urate kidney and bladder stones. It is also used in the treatment of infection with the blood parasite Leishmania.
Allopurinol is used to decreases uric acid, prevent and dissolve bladder stones.
This medication does not have an FDA approved indication for use in animals, but it is a common and acceptable practice for veterinarians to prescribe this human medication for use in animals. Make sure to tell your veterinarian what other medication you are giving to your pet. Quite often your veterinarian may prescribe two different medications, even if a drug interaction may occur. In this case, your veterinarian may vary the dose and/or monitor your pet more closely. Tell you veterinarian if you dog has a history of liver or kidney disease. The following drugs can potentially interact with allopurinol: cyclophosphamide, probenecid, sulfinpyrazone, methionine, ammonium chloride, amoxicillin, hetacillin, ampicillin, azathioprine, mercaptopurine, furosemide, thiazides, diazoxide, trimethoprim/sulfamethoxazole, warfarin, aminophylline, and theophylline. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.
Allergic reactions to medications may occur. Be sure to inform VetSource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; vomiting; widespread hives and itching.
Adverse effects in dogs are uncommon. Notify your veterinarian if your pet develops a rash or is itching excessively or becomes lethargic. Notify your veterinarian if side effects are noted and they are troublesome. Other side effects may occur. If you notice anything unusual, contact your veterinarian. The drug should be used with caution in dogs with decreased kidney function.
Allopurinol should be given orally as directed by your veterinarian. Encourage your pet to drink plenty of water and try to give this medication at about the same time each day.